The Debut of Cooper Flagg and the return of Victor Wembanyama. That alone makes you sit up and pay attention to this game as the Dallas Mavericks and the San Antonio Spurs tip off their respective seasons tonight at American Airlines Center.
Flagg, the prodigy from Duke, turned into the reward for the Mavericks trading Luka Doncic to the Lakers late last season. Wembanyama is back after missing much of last season due to a blood clot in his right shoulder.
Kyrie Irving (knee) remains sidelined for at least the first half of the season, but with the former Duke star and National Player of the Year in the lineup alongside Klay Thompson and Anthony Davis, the Mavs are expected to compete for a spot in the postseason.
The Spurs are also expected to take a step forward this season and finally compete for at least a spot in the play-in tournament. Mitch Johnson takes over as head coach for the retired Gregg Popovich. Although he is doubtful for tonight’s game De’Aaron Fox (hamstring) along with Wembanyama and last year’s Rookie of the Year Stephon Castle should help Johnson begin his tenure as head coach with some positive results. Throw in Devin Vassell and the Spurs starting lineup will be a handful for opposing teams.
We’ve got all the info and analysis you need to know ahead of the game, including the
latest info on how to catch tipoff, odds courtesy of DraftKings recent team performance, player stats, and of course, our predictions, picks best bets for the game from our modeling tools and staff of experts.
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Game Details and How to watch the Spurs vs. Mavericks live
- Date: Wednesday, October 22, 2025
- Time: 9:30PM EST
- Site: American Airlines Center
- City: Dallas, TX
- Network/Streaming: ESPN
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Game odds for the Spurs at the Mavericks
The latest odds as of Wednesday courtesy of DraftKings:
- Moneyline: San Antonio Spurs (+130), Dallas Mavericks (-155)
- Spread: Mavericks -2.5
- Total: 224.5 points
That gives the Mavericks an implied team point total of 112.44, and the Mavericks113.75.
Be sure to check out DraftKings for all the latest game odds & player props for every matchup this week on the NBA schedule!
Expected Starting Lineups
Spurs
G Stephon Castle (2024-25 Season: 81GP, 14.7ppg, 3.7reb/gm, 4.1ast/gm)
G Dylan Harper (2024-25 Preseason: 3GP, 8.7ppg, 3.7reb/gm, 4.0ast/gm)
F Harrison Barnes (2024-25 Season: 82GP, 12.3ppg, 3.8reb/gm, 1.7ast/gm)
F Devin Vassell (2024-25 Season: 64GP, 16.3ppg, 4.0reb/gm, 2.9ast/gm)
C Victor Wembanyama (2024-25 Season: 46GP, 24.3ppg, 11reb/gm, 3.7ast/gm)
Mavericks
PG D’Angelo Russell (2024-25 Season: 58GP, 12.6ppg, 2.8reb/gm, 5.1ast/gm)
G Klay Thompson (2024-25 Season: 72GP, 14ppg, 3.4reb/gm, 2.0ast/gm)
F Cooper Flagg (2024-25 Preseason: 4GP, 11.3ppg, 4.5reb/gm, 2.8ast/gm)
F Anthony Davis (2024-25 Season: 51GP, 24.7ppg, 11.6reb/gm, 3.5ast/gm)
C Dereck Lively II (2024-25 Season: 36GP, 8.7ppg, 7.5reb/gm, 2.4ast/gm)
Important stats, trends and insights ahead of Spurs at Mavericks on Wednesday.
Rotoworld Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the NBA calendar based on data points like recent performance, head-to-head player matchups, trends information and projected game totals.
Once the model is finished running, we put its projections next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for tonight’s Spurs & Mavericks game:
Want even more NBA best bets and predictions from our expert staff & tools? Check out the Expert NBA Predictions page from NBC Sports for money line, spread and over/under picks for every game on today’s calendar!
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