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White Sox vs. Orioles prediction: Odds, recent stats, trends, and best bets for June 29

It may be old news, but in case you have not heard, the White Sox (43-39) are a good baseball team in 2026. They head to Baltimore tonight holding a share of first place in the AL Central. Meanwhile, the Orioles (39-46) have been less than good at best. Their goal is to climb back into both the race in the AL East (currently 11 games behind the Rays) and the Wild Card (three games behind the final spot).

Chicago arrives after taking two of three from Kansas City over the weekend, whereas Baltimore dropped two of three at home to Washington. The White Sox’ weekend series against the Royals featured both an offensive explosion and a frustrating finish. The high point came Friday when the White Sox smacked Kansas City 22-1. Their offense failed them Saturday but their pitching carried the day in a 2-1 victory. They could not finish off the sweep yesterday, however, falling 5-4. Don’t blame Miguel Vargas for the loss, though. The Chicago slugger homered, doubled, walked twice, and scored a run.

As noted, Baltimore’s weekend against the Nationals was disappointing. The Orioles opened the series with a solid 3-1 victory Friday behind a strong performance on the mound led by Trevor Rogers. The pitching was not as sharp the rest of the weekend and the bats never arrived at the party as the O’s lost 4-3 on Saturday and 6-4 in the series finale yesterday. A positive to be drawn from yesterday’s game was the return of Adley Rutschman to the lineup. He is back not a moment too soon as the Orioles have lost four of their last five games and are searching for positives and momentum.

Tonight, the White Sox will give the ball to right-hander Sean Burke, who has quietly been one of the more consistent starters in the American League this year. Burke enters at 5-4 with a 3.71 ERA and 87 strikeouts in 87.1 innings. Over his last seven outings, Burke has posted a 3.23 ERA while holding opponents to a .216 average.

Baltimore counters with right-hander Shane Baz, who is 4-8 with a 4.31 ERA and 81 strikeouts across 94 innings. Baz took the loss in his most recent appearance, surrendering five runs in a 5-1 defeat to the Angels on June 24. That start aside, recent trends have been encouraging, as Baz has allowed three earned runs or fewer in seven of his last eight starts.

Lets dive into tonight’s matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game Details and How to Watch: White Sox vs. Orioles

  • Date: Monday, June 29, 2026
  • Time: 6:35PM EST
  • Site: Camden Yards
  • City: Baltimore, MD
  • Network/Streaming: MLB.TV, CSN, MASN

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

The Latest Odds: White Sox vs. Orioles

The latest odds as of Monday courtesy of DraftKings:

  • Moneyline: Chicago White Sox (+114), Baltimore Orioles (-137)
  • Spread: White Sox +1.5 (-179), Orioles -1.5 (+148)
  • Total: 9.5 runs

Probable Starting Pitchers and their Stats: White Sox vs. Orioles for June 29

  • White Sox: Sean Burke
    Season Totals: 87.1 IP, 5-4, 3.71 ERA, 1.21 WHIP, 87K, 30 BB
  • Orioles: Shane Baz
    Season Totals: 94.0 IP, 4-8, 4.31 ERA, 1.38 WHIP, 81K, 35 BB

Who’s Hot? Who’s Not! White Sox vs. Orioles

  • Gunnar Henderson has just one hit – a single – in his last 18 ABs
  • Pete Alonso is 5-14 with 4 runs scored and 5 RBIs over his last 4 games
  • Taylor Ward was 3-13 over the weekend against the Nationals
  • Miguel Vargas has hit safely in 6 straight games (10-23) including 3 HRs and 8 RBIs
  • Andrew Benintendi picked up at least 1 hit in each of the weekend games against the Royals (4-11)

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top Betting Trends & Insights: White Sox vs. Orioles

  • The White Sox are 47-35 on the Run Line this season
  • The Orioles are 42-43 on the Run Line this season
  • The OVER has cashed 47 times in Baltimore’s 85 games this season (47-35-3)
  • The OVER has cashed 47 times in Chicago’s 82 games this season (47-33-2)

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Expert picks & predictions: White Sox vs. Orioles

Rotoworld Bet Best Bet

Please bet responsibly. If you or someone you know has a gambling problem, call the National Gambling Helpline at 1-800-522-4700.

Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for tonight’s game between the Orioles and the White Sox:

  • Moneyline: Rotoworld Bet is recommending a play on the White Sox on the Moneyline.
  • Spread: Rotoworld Bet is leaning towards a play on the Sox on the Run Line.
  • Total: Rotoworld Bet is staying away from a play on the Game Total of 9.5

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)



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