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Knicks vs. 76ers odds, score prediction, start time: 2025 NBA picks, April 1 best bets from proven model

The New York Knicks can sweep the Philadelphia 76ers in the season series for the first time since the 2015-16 season with a victory on Tuesday. The Knicks have won four of their last five games overall as they move closer to clinching the No. 3 seed in the Eastern Conference. New York is 47-27 overall and 25-12 at home, while Philadelphia is 23-52 and 11-27 on the road. The 76ers have lost eight straight games in what’s been an injury-riddled, lost season for one of the most consistent teams in the Eastern Conference over the last few years. 

Tipoff is set for 7:30 p.m. ET from Madison Square Garden. The Knicks are 14.5-point favorites in the latest Knicks vs. 76ers odds, according to the SportsLine consensus. The over/under is 223.5 points. Before entering any 76ers vs. Knicks picks, you’ll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 24 of the 2024-25 NBA season on a sizzling 155-115 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It’s also an outstanding 21-10 (68%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on New York vs. Philadelphia. You can head to SportsLine to see its picks. Here are several NBA betting lines for 76ers vs. Knicks:

  • Knicks vs. 76ers spread: Knicks -14.5 at Caesars Sportsbook
  • Knicks vs. 76ers over/under: 223.5 points
  • Knicks vs. 76ers money line: Knicks -1075, 76ers +685
  • PHI: The Over is 7-2 over the last nine 76ers games
  • NYK: The Knicks are 4-1 against the spread (ATS) over their last five games
  • Knicks vs. 76ers picks: See picks at SportsLine
  • Knicks vs. 76ers streaming: FuboTV (try for free)

Why the 76ers can cover

The 76ers are hurting, but so are the Knicks. New York point guard Jalen Brunson was cleared for basketball activities after suffering an ankle injury, but he remains out for Tuesday. Still, the Knicks are double-digit point favorites on Tuesday and New York is just 2-3 ATS over their last five games when favored by at least 10 points.

Quentin Grimes has had a few monstrous performances for the 76ers over the last few weeks, and with Tuesday being a revenge game against his former team, the 24-year-old could be additionally motivated to have one of his better outputs. Grimes spent his first three seasons with the Knicks before being traded to the Pistons. Grimes scored at least 30 points in four games in March and Philadelphia either won or lost by single digits in three of those contests. See which team to pick here.

Why the Knicks can cover

The 76ers enter on an eight-game losing streak and have failed to cover the spread as the underdog in seven of those eight losses. Philadelphia allowed at least 118 points in seven of those games and has been held to fewer than 100 points in two of its last four contests. Kelly Oubre Jr. (knee) and Andre Drummond (toe) remain out for the 76ers who are already without their star trio of Joel Embiid, Paul George and Tyrese Maxey. Meanwhile, besides Brunson out, the core of OG Anunoby, Karl-Anthony Towns, Mikal Bridges and Josh Hart are off the injury report.

The 76ers had a four-year stretch where they won 15 straight games against the Knicks from the 2017-18 season through the 2020-21 season. Although none of the current core played on those Knicks teams, the fans who will be at Madison Square Garden certainly remember that and won’t want the Knicks to let up against the 76ers, even if they are up by a large margin. The Knicks are 4-1 over their last five games with three wins coming by at least 15 points, led by OG Anunoby averaging 30.5 ppg over his last four contests. See which team to pick here.

How to make Knicks vs. 76ers picks

The model has simulated 76ers vs. Knicks 10,000 times and the results are in. The model is leaning Over, projecting 226 points, and it also says one side of the spread hits well over 50% of the time. You can only see the pick at SportsLine.

So who wins Knicks vs. 76ers, and which side of the spread hits in well over 50% of simulations? Visit SportsLine now to see which side of the 76ers vs. Knicks spread you need to jump on, all from the model that is on a 155-115 roll on top-rated NBA picks since last season, and find out.

Where to bet on NBA games

Here are some of the sportsbooks to bet on NBA games today, along with the various NBA sportsbook promos they currently offer.



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