The Detroit Lions will begin their quest to reach their first-ever Super Bowl when they take on the upstart Washington Commanders in a 2025 NFL Divisional Round matchup on Saturday. Washington is coming off a last-second 23-20 win over the Tampa Bay Buccaneers in the Wild Card Round, while Detroit had the lone NFC bye. The Commanders (12-5), second in the NFC East, have won five in a row and are 5-3 on the road. The Lions (15-2), who won the NFC North for the second consecutive season, are 7-2 on their home field in 2024-25.
Kickoff from Ford Field in Detroit is set for 8 p.m. ET. The Lions are 9.5-point favorites in the latest Lions vs. Commanders odds from the SportsLine Consensus, up two from the opener, while the over/under for total points scored is 55.5, up six from the opening line. Before making any Lions vs. Commanders picks, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model, as well as everything else that SportsLine has to help you crush your NFL picks.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the Divisional Round of the 2025 NFL playoffs on a 31-15 betting hot streak on top-rated NFL picks this year, a stunning 67% success rate. Longer term, it is on a 211-143 roll on top-rated NFL picks that dates back to the 2017 season and a 65-36 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps could have seen strong returns.
In addition to the model picks for this game, you can get AI props, Vegas expert picks, DFS Optimizer lineups, and everything else you need to crush your NFL Wild Card Weekend bets. Go to SportsLine now to see it all.
Now, the model has set its sights on Commanders vs. Lions and just locked in its NFL picks and NFL predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and NFL betting lines for Lions vs. Commanders:
- Lions vs. Commanders spread: Lions -9.5
- Lions vs. Commanders over/under: 55.5 points
- Lions vs. Commanders money line: Commanders +394, Lions -532
- WASH: Commanders are 5-5 against the spread in their last 10 games
- DET: Lions are 6-4 ATS in their last 10 games
- Lions vs. Commanders picks: See picks at SportsLine
- Lions vs. Commanders streaming: FuboTV (Try for free)
Why the Lions can cover
Quarterback Jared Goff, who is in the MVP conversation, completed 390 of 539 passes (72.4%) for 4,629 yards and 37 touchdowns with 12 interceptions and a 111.8 rating. He has thrown for 300 or more yards in six games.
Goff’s top target in the passing game is veteran wide receiver Amon-Ra St. Brown. In 17 games, he has 115 receptions for 1,263 yards (11.0 average) and 12 touchdowns with 14 explosive plays of 20 or more yards, including a long of 66. He has 412 yards after the catch with 72 first-down conversions. See which side to pick here.
Why the Commanders can cover
Rookie quarterback Jayden Daniels has been on fire this season. In 17 regular-season games, Daniels completed 69% of his passes for 3,568 yards and 25 touchdowns with nine interceptions and a 100.1 rating. He was also Washington’s top rusher, carrying 148 times for 891 yards (6.0 average) and six touchdowns.
Veteran wide receiver Terry McLaurin is the Commanders’ top pass-catcher. In 17 regular-season games, he caught 82 passes for 1,096 yards (13.4 average) and 13 touchdowns. He had 12 explosive plays of 20 yards or more, including a long of 86, with 292 yards after the catch and 56 first-down conversions. See which side to pick here.
How to make Commanders vs. Lions picks
The model is going over the total, calling for 59 total points, and it also says one side of the spread cashes in nearly 60% of simulations. You can only get the NFL model’s picks at SportsLine.
So who wins Commanders vs. Lions on Saturday, and which side of the spread cashes almost 60% of the time? Visit SportsLine now to see which side of the Commanders vs. Lions spread to jump on, all from the advanced model that is up well over $7,000 on its NFL picks, and find out, and don’t forget to unlock AI props, Vegas expert picks, DFS Optimizer lineups, and all the other tools to crush your picks at SportsLine.
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