Day 2 of the 2025 MLB season doesn’t bring that same child-like excitement as Opening Day to millions across America, but it is the true sign that baseball is back. One of the aspects baseball fans love about the MLB season is once it starts, your favorite team plays almost every day. For daily Fantasy baseball players, you truly have games every day with the chance to make new MLB DFS lineups based on the day’s matchups and with a 10-game MLB slate for Friday, how should you form an MLB DFS strategy on sites like FanDuel and DraftKings?
The Baltimore Orioles had the top Opening Day offensive performance with 12 runs scored, so should you expect that to continue and build an MLB DFS stack around Orioles in the MLB DFS player pool like Adley Rutschman, Tyler O’Neill and Jordan Westburg? Before locking in any MLB DFS picks for Friday, be sure to check out the MLB DFS advice, strategy and projections from SportsLine daily Fantasy expert Mike McClure.
McClure is a daily Fantasy pro who has won more than $2 million in his career. And when it comes to daily Fantasy baseball, McClure is at his best. Recognized in the book “Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune” as a top MLB DFS player, McClure’s proprietary projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.
On Opening Day, McClure identified Angels catcher Logan O’Hoppe as one of his top MLB DFS picks on both sites. The result: O’Hoppe went 2-for-4 with a home run, returning 21.7 points on FanDuel and 17 points on DraftKings. Anybody who included him in their lineups could have been well on the way to a profitable day.
Now, with the 2025 MLB continuing on Friday, McClure has locked in his top MLB daily Fantasy picks for March 28. You can head to SportsLine now to see them.
McClure’s top MLB DFS picks for Friday, March 28
One of McClure’s top MLB DFS picks for Friday is Mets outfielder Juan Soto at $6,000 on DraftKings and $4,400 on FanDuel for MLB DFS lineups. The man with the richest contract in professional sports history had the chance to be a true hero in his very first game. Although Soto failed in that moment by striking out with two runners on and trailing by two runs, he still went 1-for-3 with two walks on Thursday.
McClure doesn’t expect that one strikeout to linger long. Soto signed a 15-year, $765 million deal with the Mets this offseason after having 41 home runs, 109 RBI and 121 runs scored for the Yankees last year. The Astros are starting right-handed pitcher Hunter Brown and the left-handed hitting Soto is 2-for-5 with a double over his career against Brown. Mets fans will quickly forget about that one strikeout from one of the top players in the sport and McClure expects a solid Friday performance to start that.
McClure is also rostering Astros catcher/first baseman Yainer Diaz ($4,200 on DraftKings and $2,900 on FanDuel). Diaz went 1-for-3 with a walk and an RBI on Opening Day after hitting .299 with 16 home runs and 84 RBI last season. The 26-year-old had a decrease in slugging and home run total in 2024 from 2023, but he increased his batting average and on-base percentage as the young catcher shapes into an all-around offensive threat. Diaz had the fourth-best OPS (.766) of any catcher who had at least 450 at-bats last season.
The Mets are starting Tylor Megill against the Astros on Friday and Megill has a 4.54 career ERA as a starter as he’s been used as both a starter and a reliever at different points in New York. Megill has a tough postseason, allowing five runs over 4 1/3 innings for a 10.38 ERA, including allowing two home runs and four runs over three innings against the Dodgers in the NLCS. Friday will be his first time in meaningful action since that performance. See McClure’s full MLB DFS player pool right here.
How to set your MLB DFS lineups for March 28, 2025
McClure is also targeting an undervalued player who is set to explode for huge numbers on Friday. The stars are aligning for him to return tournament-winning value and he comes at a price that won’t break the bank. You can only see who it is, and get the rest of McClure’s MLB DFS picks, here.
So what are the top MLB DFS picks for Friday? Visit SportsLine now to see DFS millionaire Mike McClure’s complete player pool and picks for FanDuel and DraftKings, all from the DFS expert who has won more than $2 million.
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