The Milwaukee Brewers battle the New York Yankees in a 2025 MLB Opening Day matchup on Thursday afternoon. Milwaukee won the National League Central at 93-69 last season, while New York won the American League East at 94-68. The Brewers, who have won their division each of the past two seasons, were 46-35 on the road in 2024. The Yankees, who won the AL East in two of the past three years, were 44-37 at home last season.
First pitch from Yankee Stadium is set for 3:05 p.m. ET. The Yankees won two of three meetings a year ago, with New York outscoring Milwaukee 36-15. New York is a -144 favorite on the money line (risk $144 to win $100) in the latest Yankees vs. Brewers odds from SportsLine consensus, while the Brewers are +121 underdogs. The over/under, or total number of runs Vegas thinks will be scored, is 8. Yankees starting pitcher Carlos Rodon is +130 to throw seven or more strikeouts. Before making any Brewers vs. Yankees picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters the 2025 MLB season on a 32-17 roll on top-rated run-line betting picks (+699) that dates back to 2023. Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Brewers vs. Yankees and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several MLB odds and betting lines for Yankees vs. Brewers:
- Yankees vs. Brewers money line: New York -140, Milwaukee +118 at Caesars Sportsbook
- Yankees vs. Brewers over/under: 8 runs
- Yankees vs. Brewers run line: New York -1.5 (+135)
- MIL: The Brewers have hit the money line in 21 of their last 31 road games (+10.80 units)
- NYY: The Yankees have hit the game total over in 69 of their last 119 games (+19.05 units)
- Yankees vs. Brewers picks: See picks at SportsLine
- Yankees vs. Brewers streaming: FuboTV (Try for free)
Why the Yankees can cover
New York is expected to send 32-year-old Carlos Rodon to the mound. The left-hander started 32 games a year ago, posting a 16-9 record with a 3.96 ERA. In 175 innings pitched, he allowed 157 hits, 77 earned runs with 57 walks and 195 strikeouts. In the postseason, he was 1-2 with a 5.60 ERA. In four career starts against Milwaukee, he is 1-1 with a 2.65 ERA, allowing five earned runs in 17 innings.
Helping power the offense is center fielder Aaron Judge. In 158 games in 2024, he batted .322 with 36 doubles, one triple, 58 homers, 122 runs scored and 144 RBI. In limited action, he has hit Milwaukee well. In 12 games against the Brewers, he is hitting .378 with two doubles, five homers and 10 RBI. He was 5-for-12 with two homers and five RBI in three games at Milwaukee last season. See which team to back at SportsLine.
Why the Brewers can cover
Right-hander Freddy Peralta (11-9, 3.68 ERA) was named Milwaukee’s starter on the first day of spring training. The 28-year-old enters his eighth season with the Brewers. Last season, he made 32 starts, pitching 173.2 innings, allowing 71 earned runs, while walking 68 and striking out 200. In 178 career games, including 129 starts, he is 53-36 with a 3.79 ERA. He will be making his first-ever start at Yankee Stadium.
Veteran left fielder Christian Yelich enters the season healthy after having back surgery toward the end of the 2024 season. He has been the heart of the offense over the past seven seasons. In 73 games last year before being shut down, he hit .315 with 12 doubles, three triples, 11 homers and 42 RBI. In eight career games against New York, he hit .323 with one double, one homer and three RBI. See which team to back at SportsLine.
How to make Yankees vs. Brewers picks
SportsLine’s model is leaning Over on the total, and it says one side of the money line has all the value. You can head to SportsLine to see the model’s MLB picks.
So who wins Brewers vs. Yankees on MLB Opening Day, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.
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