The St. Louis Cardinals (56-58) and New York Yankees (64-50) meet tonight in the rubber game of their three-game series at Yankee Stadium. After being smacked 13-7 in Monday’s opener, the norm returned for the Yankees – elite starting pitching and just enough offense – as the Bronx Bombers blanked the Cardinals 2-0.
The story of the game was the major-league debut of highly regarded Yankees prospect George Lombard Jr. The 21-year-old shortstop delivered the defining moment of the night in the fifth inning when he launched a solo home run into the left-field seats off Cardinals’ starter Hunter Dobbins. The blast was Lombard’s first major-league hit and made him the first Yankees shortstop ever to homer in his MLB debut. New York’s other run came on a second-inning home run by Jazz Chisholm Jr. That was enough for left-hander Ryan Weathers who delivered one of his best outings of the season. He worked six scoreless innings, allowed just four hits, struck out six, and did not issue a walk. It was the Yankees American League-leading 12th shutout of the season.
St. Louis is expected to start right-hander Andre Pallante (11-6, 3.72 ERA) tonight while the Yankees plan to send Will Warren (8-5, 4.14 ERA) to the bump. Warren blanked the Cubs at Wrigley last Friday over 6.2 innings. Pallante’s last start was also against the Cubs. The righthander allowed two runs over 6.1 innings.
Lets dive into tonight’s matchup and find a sweat or two.
We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.
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Game Details and How to Watch: Cardinals vs. Yankees
- Date: Wednesday, August 5, 2026
- Time: 7:05PM EST
- Site: Yankee Stadium
- City: New York, NY
- Network/Streaming: MLB.TV, Cardinals.TV, Prime Video
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The Latest Odds: Cardinals vs. Yankees – August 5
The latest odds as of Wednesday courtesy of DraftKings:
- Moneyline: St. Louis Cardinals (+137), New York Yankees (-146)
- Spread: Cardinals +1.5 (-158), Yankees -1.5 (+131)
- Total: 8.5 runs
Starting Pitchers and their Stats: Cardinals vs. Yankees for August 5
- Cardinals: Andre Pallante
Season Totals: 118.2 IP, 11-6, 3.72 ERA, 1.22 WHIP, 86K, 34 BB - Yankees: Will Warren
Season Totals: 108.2 IP, 8-5, 4.14 ERA, 1.36 WHIP, 109K, 36 BB
Who’s Hot? Who’s Not! Cardinals vs. Yankees
- Ben Rice is 0-11 in August and 1 for his last 18
- Jazz Chisholm Jr. homered last night to snap an 0-12 streak the previous 3 games
- Alec Burleson is 2-4 in his career against Will Warren
- Trent Grisham is 3-9 in this series
- JJ Wetherholt is 1-13 over his last 4 games
- Masyn Winn is 2-14 in August
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Top Betting Trends & Insights: Cardinals vs. Yankees
- The Cardinals are 61-53 on the Run Line this season
- The Yankees are 54-60 on the Run Line this season
- The OVER has cashed an MLB-worst 44 times in games involving the Cardinals this season (44-64-6)
- The OVER has cashed 49 times in games involving the Yankees this season (49-61-4)
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Expert picks & predictions: Cardinals vs. Yankees
Rotoworld Bet Best Bet
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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.
Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.
Here are the best bets our model is projecting for tonight’s game between the Cardinals and the Yankees:
- Moneyline: Rotoworld Bet is staying away from a play on the Moneyline.
- Spread: Rotoworld Bet is leaning towards a play on the Yankees on the Run Line.
- Total: Rotoworld Bet is leaning towards a play on the Game Total UNDER 8.5.
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