MLB

Cubs vs Brewers Prediction: Odds, recent stats, trends, and best bets for June 26

The NL Central is heating up as Milwaukee (49-29) and Chicago (44-37) both have winning streaks on the line when they meet at the American Family Field for the first of a three game series. The two met earlier this season and Milwaukee is 3-0 versus Chicago outscoring the Cubs, 19-5.

The Brewers are heating up with four straight wins and seven of the past 10. Milwaukee is coming off a sweep over Cincinnati, outscoring the Reds, 10-6 across three games. turns to their ace and the Cy Young favorite, Jacob Misiorowski. Milwaukee is 5-1 in his last six starts and are 7-2 in the past nine. Misiorowski is on a streak of nine straight games with two earned runs or less. He didn’t allow a single run versus Chicago earlier this season over six innings (8 Ks, 1 BB, 3 H).

Chicago has also won four straight games and are 6-1 over the past seven contests with an 8-6 loss as the only blemish. The Cubs swept the Mets over a four-game series putting up 33 total runs to New York’s 17. Chicago’s offense is hitting .252 in June (15th), but own the third-most walks (89) and the fifth-most stolen bases (20).

Let’s dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Cubs at Brewers

  • Date: Friday, June 26, 2026
  • Time: 7:45 PM EST
  • Site: American Family Field
  • City: Milwaukee, WI
  • Network/Streaming: Apple TV

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Cubs at the Brewers

The latest odds as of Friday:

  • Moneyline: Chicago Cubs (+198), Milwaukee Brewers (-245)
  • Spread: Brewers +1.5 (-109), Cubs -1.5 (-110)
  • Total: 7.0

Probable starting pitchers for Cubs at Brewers

  • Friday’s pitching matchup (June 26): Colin Rea vs. Jacob Misiorowski
  • Cubs: Colin Rea

2026 stats: 79.1 IP, 5-5, 4.99 ERA, 1.40 WHIP, 59 Ks, 28 BB

2026 Stats: 93.0 IP, 8-3, 1.45 ERA, 0.75 WHIP, 138 Ks, 23 BB

Who’s Hot? Who’s Not

  • The Cubs’ Pete Crow-Armstrong is hitting .287 with 88 hits, 17 home runs and 45 RBI over 307 at-bats
  • The Cubs’ Ian Happ is hitting .229 with 66 hits and 106 strikeouts over 288 at-bats
  • The Brewers’ William Contreras is hitting .302 with 87 hits, 8 home runs, and 48 RBI over 288 at-bats
  • The Brewers’ Garrett Mitchell is hitting .248 with 53 hits and 85 strikeouts over 228 at-bats

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Cubs at Brewers

  • The Cubs are 32-49 ATS, ranking third-worst
  • The Brewers are 44-34 ATS, ranking fifth-best
  • The Cubs are 43-37-1 to the Over, ranking eighth-best
  • The Brewers are 41-35-2 to the Under, ranking fifth-best
  • The Cubs are 18-23 ATS, ranking seventh-worst
  • The Brewers are 23-17 ATS, ranking fifth-best

Expert picks & predictions for tonight’s game between the Cubs and the Brewers

Rotoworld Bet Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Friday’s game between the Cubs and the Brewers:

  • Moneyline: NBC Sports Bet is recommending a play on the Brewers on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Brewers at -1.5.
  • Total: NBC Sports Bet is recommending a play on the Under on the Game Total of 7.0

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)



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