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Dodgers vs Padres Prediction: Odds, recent stats, trends, and best bets for May 18

The Dodgers (29-18) and Padres (28-18) meet for a three-game series at Petco Park as both enter two of the hotter teams in the MLB. This is the first meeting of the season between the NL West opponents.

Los Angeles is on a five-game winning streak after sweeping the Angels and taking two of four against the Giants. Over the past week, the Dodgers are hitting .254 (11th), while the pitching staff ranks second in ERA (1.83) with the best OBA (.171). Yoshinobu Yamamoto takes the mound for the Dodgers tonight and Los Angeles is 5-3 in his eight starts.

San Diego is coming off a three-game sweep of Seattle and have won four of the past five games. The Padres outscored the Mariners 17-7 in the series and scored 15 combined runs in the past two games. On the mound, Michael King will start for San Diego. King is coming off two straight games of one earned run and has two or fewer in seven out of nine games, but the Padres are 4-5 in his starts.

Let’s dive into the matchup and find a sweat or two.

We’ve got all the info and analysis you need to know ahead of the game, including the latest info on the how to catch first pitch, odds, recent team performance, player stats, and of course, our predictions, picks & best bets for the game from our modeling tools and staff of experts.

Follow Rotoworld Player News for the latest fantasy and betting player news and analysis all season long.

Game details & how to watch Dodgers at Padres

  • Date: Monday, May 18, 2026
  • Time: 9:40 PM EST
  • Site: Petco Park
  • City: San Diego, CA
  • Network/Streaming: MLB TV

Never miss a second of the action and stay up-to-date with all the latest team stats and player news. Check out our day-by-day MLB schedule page, along with detailed matchup pages that update live in-game with every out.

Odds for the Dodgers at the Padres

The latest odds as of Monday:

  • Moneyline: Los Angeles Dodgers (-155), San Diego Padres (+128)
  • Spread: Padres +1.5 (-137), Dodgers -1.5 (+114)
  • Total: 7.5

Probable starting pitchers for Dodgers at Padres

  • Monday’s pitching matchup (May 18): Yoshinobu Yamamoto vs. Michael King
  • Dodgers: Yoshinobu Yamamoto

2026 stats: 50.0 IP, 3-3, 3.60 ERA, 1.00 WHIP, 48 Ks, 10 BB

2026 Stats: 51.1 IP, 3-2, 2.63 ERA, 1.09 WHIP, 50 Ks, 22 BB

Who’s Hot? Who’s Not!

  • The Padres’ Miguel Andujar is hitting .291 with 37 hits and 61 total bases over 127 at-bats
  • The Padres’ Jackson Merrill is hitting .206 with 35 hits and 49 strikeouts over 170 at-bats
  • The Dodgers’ Andy Pages is hitting .301 with 52 hits and 90 total bases over 173 at-bats
  • The Dodgers’ Shohei Ohtani is hitting .258 with 42 hits and 48 strikeouts over 163 at-bats

Rotoworld still has you covered with all the latest MLB player news for all 30 teams. Check out the feed page right here on NBC Sports for headlines, injuries and transactions where you can filter by league, team, positions and news type!

Top betting trends & insights to know ahead of Dodgers at Padres

  • The Padres are 20-25-1 ATS and to the Under this season
  • The Dodgers are 21-26 ATS and to the Under this season
  • The Padres are 6-4 ATS and 5-5 on the ML as a home underdog
  • The Dodgers are 14-8 ATS as a road favorite, ranking second-best
  • The Padres are 6-4 to the Over as a home underdog
  • The Dodgers are 11-11 as a road favorite

If you’re looking for more key trends and stats around the spread, moneyline and total for every single game on the schedule today, check out our MLB Top Trends tool on NBC Sports!

Expert picks & predictions for tonight’s game between the Dodgers and the Padres

Rotoworld Bet Best Bet

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Our model calculates projections around each moneyline, spread and over/under bet for every game on the MLB calendar based on data points like past performance, player matchups, ballpark information and weather forecasts.

Once the model is finished running, we put its projection next to the latest betting lines for the game to arrive at a relative confidence level for each wager.

Here are the best bets our model is projecting for Monday’s game between the Dodgers and the Giants.

  • Moneyline: NBC Sports Bet is recommending a play on the Dodgers on the Moneyline.
  • Spread: NBC Sports Bet is leaning towards a play ATS on the Dodgers at -1.5.
  • Total: NBC Sports Bet is recommending a play on the Under on the Game Total of 7.5

Follow our experts on socials to keep up with all the latest content from the staff:

  • Jay Croucher (@croucherJD)
  • Drew Dinsick (@whale_capper)
  • Vaughn Dalzell (@VmoneySports)
  • Trysta Krick (@Trysta_Krick)



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